Search results for "Sistema nervioso"

showing 10 items of 27 documents

Estudio de la migración neuronal de las células nerviosas de la SVZ en la enfermedad de Alzheimer

2021

En el cerebro adulto de la mayoría de los mamíferos el nicho neurogénico con mayor capacidad neurogénica es la zona ventricular-subventricular (V-SVZ). Esta región se encuentra distribuida a lo largo de las paredes de los ventrículos laterales. La capacidad neurogénica que presenta esta región se debe a la presencia de las denominadas células B. Además nos encontramos con otros tipos celulares como son las células tipo C o progenitores intermedios, las tipo A o migradoras y las tipo E o células ependimarias. Las células tipo B son capaces de dar lugar a las células tipo C que finalmente generan las células tipo A. En condiciones fisiológicas, las células tipo A migran principalmente hasta l…

:CIENCIAS DE LA VIDA::Neurociencias::Neurofisiología [UNESCO]migración:CIENCIAS MÉDICAS ::Patología::Neuropatología [UNESCO]:CIENCIAS DE LA VIDA::Fisiología humana ::Fisiología del sistema nervioso central [UNESCO]alzheimerneurogénesissenescenciaSVZUNESCO::CIENCIAS DE LA VIDA::Neurociencias::NeurofisiologíaUNESCO::CIENCIAS MÉDICAS ::Patología::NeuropatologíaAPC/C-Cdh1UNESCO::CIENCIAS DE LA VIDA::Fisiología humana ::Fisiología del sistema nervioso central
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Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycl…

2009

Background The prevalence of and risk factors for central nervous system recurrence in patients with acute promyelocytic leukemia are not well established and remain a controversial matter. Design and Methods Between 1996 and 2005, 739 patients with newly diagnosed acute promyelocytic leukemia enrolled in two consecutive trials (PETHEMA LPA96 and LPA99) received induction therapy-with all-trans retinoic acid and idarubicin. Consolidation therapy comprised three courses of anthracycline monochemotherapy (LPA96), with all-trans retinoic acid and reinforced doses of idarubicin in patients with an intermediate or high risk of relapse (LPA99). Central nervous system prophylaxis was not given. Re…

:Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons Cyclic::Hydrocarbons Aromatic::Polycyclic Hydrocarbons Aromatic::Naphthacenes::Anthracyclines::Daunorubicin::Idarubicin [Medical Subject Headings]:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Recurrence [Medical Subject Headings]Male:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]idarubicinGastroenterology:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Central Nervous System NeoplasmsLeukemia Promyelocytic AcuteRecurrenceRisk FactorsCumulative incidenceAntibiotics AntineoplasticHematologyMiddle Agedall-trans retinoic acidLeukemiamedicine.anatomical_structure:Named Groups::Persons::Age Groups::Adolescent [Medical Subject Headings]Femalemedicine.drugAcute promyelocytic leukemiaAdultcentral nervous system relapsemedicine.medical_specialty:Diseases::Neoplasms::Neoplasms by Histologic Type::Leukemia::Leukemia Myeloid::Leukemia Myeloid Acute [Medical Subject Headings]AnthracyclineAdolescentCentral nervous system:Check Tags::Male [Medical Subject Headings]TretinoinNeoplasias del sistema nervioso centralCentral nervous system diseaseTretinoinInternal medicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]medicineIdarubicinHumans:Named Groups::Persons::Age Groups::Adult::Aged [Medical Subject Headings]Letters to the Editor:Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons Acyclic::Alkenes::Polyenes::Carotenoids::Retinoids [Medical Subject Headings]Leucemia promielocítica agudaAgedAntibióticos antineoplásicosbusiness.industryprognostic factors:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents::Antibiotics Antineoplastic [Medical Subject Headings]acute promyelocytic leukemiamedicine.diseaseSurgery:Diseases::Neoplasms::Neoplasms by Site::Nervous System Neoplasms::Central Nervous System Neoplasms [Medical Subject Headings]:Check Tags::Female [Medical Subject Headings]businessIdarubicin
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Clinical and therapeutic features of myasthenia gravis in adults based on age at onset

2020

[Objective] To describe the characteristics of patients with very-late-onset myasthenia gravis (MG).

AdultMalePediatricsmedicine.medical_specialtyThymomagenetic structuresCross-sectional studyInvestigación médicaEnfermedad del sistema nerviosoMEDLINEMiastenia gravisLate onsetDISEASECLASSIFICATIONArticleACETYLCHOLINE-RECEPTOR03 medical and health sciences0302 clinical medicineimmune system diseasesMyasthenia GravismedicineEnfermedades neuromuscularesHumansRITUXIMAB030212 general & internal medicineAge of OnsetAgedbusiness.industryAnálisis de datosMiddle Agedmedicine.diseaseMyasthenia gravisnervous system diseasesCross-Sectional StudiesTreatment OutcomeMulticenter studyANTIBODIESAUTOANTIBODIESFemaleObservational studyNeurology (clinical)Age of onsetbusiness030217 neurology & neurosurgeryMUSK
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Efectos de la exposición crónica al etanol sobre el tráfico intracelular y citoesqueleto como factores implicados en la migración neuronal

2013

El consumo de etanol durante la gestación puede inducir una serie de alteraciones graves en el desarrollo del feto, la manifestación más extrema da lugar al Síndrome Alcohólico Fetal (SAF). La exposición prenatal al alcohol es la causa conocida y, además evitable, más importante de retraso mental en el mundo occidental. Además de déficits cognitivos, los niños con SAF presentan múltiples anomalías estructurales en el sistema nervioso central, como reducción de la masa cerebral, y a nivel celular, daños en la migración neuronal, en el proceso de formación de espinas dendríticas y establecimiento de sinapsis. En la actualidad, los mecanismos moleculares implicados en la teratogénesis inducida…

Central Nervous Systemaparato de Golgietanolespinas dendríticasneuronasneurons:CIENCIAS DE LA VIDA::Neurociencias [UNESCO]migración neuronalMAP2Fetal Alcoholic SyndromeRho GTPasasactinaRho GTPasesendocitosis:CIENCIAS MÉDICAS::Toxicología [UNESCO]endocytosismicrotúbuloneuronal migrationUNESCO::CIENCIAS MÉDICAS::Toxicologíatráfico intracelularUNESCO::CIENCIAS DE LA VIDA::Biología celular::Cultivo celularcytoskeletondendritic spinesSAFSíndrome Alcohólico Fetalcitoesqueleto:CIENCIAS DE LA VIDA::Biología celular::Cultivo celular [UNESCO]Golgi apparatusUNESCO::CIENCIAS DE LA VIDA::Neurocienciasethanolintracellular trafficactinSistema Nervioso Centralmicrotubule
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Neuroprotective potential of Ginkgo biloba in retinal diseases

2019

AbstractLike other tissues of the central nervous system, the retina is susceptible to damage by oxidative processes that result in several neurodegenerative disease such as age-related macular degeneration, diabetic retinopathy, glaucoma, ischaemic retinal disease, retinal disease produced by light oxidation, and detached retina, among other diseases. The use of antioxidant substances is a solution to some health problems caused by oxidative stress, because they regulate redox homeostasis and reduce oxidative stress. This is important for neurodegeneration linked to oxidation processes. In line with this, Ginkgo biloba is a medicinal plant with excellent antioxidant properties whose effect…

Ginkgo biloba - Uso terapéutico.Pharmaceutical SciencePharmacologymedicine.disease_cause01 natural sciencesNeuroprotectionAnalytical Chemistrychemistry.chemical_compoundRetinal DiseasesGinkgo biloba - Therapeutic use.Drug DiscoveryAnimalsHumansMedicinePharmacologyRetinabiologyPlant Extracts010405 organic chemistrybusiness.industryGinkgo bilobaRetina - Diseases - Treatment.System nervous - Degeneration - Treatment.Organic ChemistryNeurodegenerationGinkgo bilobaNeurodegenerative DiseasesRetinalDiabetic retinopathyMacular degenerationmedicine.diseasebiology.organism_classificationEye - Diseases - Treatment.0104 chemical sciencesSistema nervioso - Degeneración - Tratamiento.010404 medicinal & biomolecular chemistryNeuroprotective Agentsmedicine.anatomical_structureComplementary and alternative medicinechemistryOjos - Enfermedades - Tratamiento.Molecular MedicinebusinessOxidative stressPhytotherapyRetina - Enfermedades - Tratamiento.
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A strategy to improve the comprehension and learning in morphological science: Powerpoint presentation

2003

In this paper, a hypertext to the Morphological Sciences in biological area was developed and evaluated. The application with format of digital atlas approaches  Anatomical, Histological and Functional concepts about  the man and  animals in integrated form. PowerPoint presentation was developed to operators which experience in the handling of software are limited. This digital resource was qualified as a good complement of other didactic materials. In this knowledge area offers opportunity  to develop significant knowledge to improve the understanding and  learning through an interactive methodology.

Hipertexto Evaluación Aprendizaje Compresión Ciencias Morfológicas Sistema Nervioso Desarrollo Humano
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Impact of the Relationship of Stress and the Immune System in the Appearance of Alzheimer’s Disease

2016

The understanding of how the immune system works, as well as its relationship with the stress level, seems to be important at the start of the Alzheimer’s disease (AD). To analyze this, immunoglobulin A (IgA) and cortisol in saliva were measured using ELISA in patients with mild AD and healthy volunteers, and the production of both biomarkers was compared and correlated. In participants without AD, IgA was higher when cortisol was lower, and the opposite happened in participants with AD, with the quantification in saliva being a suitable method to determine it. Sin financiación 1.635 SJR (2017) Q1, 12/108 Geriatrics and Gerontology, 239/2885 Medicine (miscellaneous), 64/529 Psychiatry and M…

Immunoglobulin AMaleSalivaHydrocortisoneEnfermedad del sistema nerviosoDiseaseStatistics NonparametricStress level03 medical and health sciences0302 clinical medicineImmune systemAlzheimer DiseaseEnfermedad de AlzheimermedicineHumansIn patientSalivaHydrocortisoneAgedEstrésbiologybusiness.industryGeneral NeuroscienceEstrés mentalGeneral Medicinemedicine.disease030227 psychiatryImmunoglobulin APsychiatry and Mental healthClinical PsychologyEfectos fisiológicosImmune SystemImmunologybiology.proteinFemaleGeriatrics and GerontologyAlzheimer's diseasebusiness030217 neurology & neurosurgeryStress Psychologicalmedicine.drug
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Slackline Training in Children with Spastic Cerebral Palsy: A Randomized Clinical Trial

2020

Objective: To assess whether a slackline intervention program improves postural control in children/adolescents with spastic cerebral palsy (CP). Design: Randomized controlled trial. Setting: Patients&rsquo

Malemedicine.medical_specialtyAdolescentHealth Toxicology and MutagenesisMovementSignificant groupMotor DisordersTerapéuticalcsh:Medicineneuro-disabilityArticlelaw.inventionrehabilitation03 medical and health sciencesTratamiento médico0302 clinical medicineSpastic cerebral palsyRandomized controlled triallawSpasticMedicineHumansChildPostural BalanceMotor skillRating of perceived exertionIntervention programexerciseSistema nerviosobusiness.industryElectromyographyCerebral PalsyPosturographylcsh:RPublic Health Environmental and Occupational HealthResistance Training030229 sport sciencesmedicine.diseaseEnfermedadesNiños paralíticos cerebralesTreatment OutcomeMotor SkillsMuscle SpasticityPhysical therapynon-conventional balance therapyFemalebusiness030217 neurology & neurosurgery
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Effects of progressive resistance exercise in akinetic-rigid Parkinson's disease patients: a randomized controlled trial.

2017

Progressive resistance exercise (PRE) can have a positive effect in individuals with Parkinson’s disease (PD). However, the effect of PRE may vary with the clinical subtype of PD. To date, no study has assessed the effects of PRE in the different subtypes of PD. AIM: The aim of the present study was to assess the effects of PRE in PD patients with akinesia and rigidity (AR-subtype). DESIGN: A randomized controlled trial was conducted. SETTING: Outpatients clinics of the Bierzo Parkinson Association (Ponferrada, Spain) and the Asturias Parkinson Association (Oviedo, Spain). POPULATION: Twenty-eight patients with AR-subtype PD were randomized into an Experimental Group (EG, N.=13) and Control…

Malemedicine.medical_specialtyMovement disordersParkinson's diseasemedicine.medical_treatmentCondición física - EjerciciosPopulationEnfermedad del sistema nerviosoPhysical Therapy Sports Therapy and RehabilitationRisk Assessmentlaw.invention03 medical and health sciencesTratamiento médico0302 clinical medicineRhythmPhysical medicine and rehabilitationRandomized controlled triallawRating scaleReference ValuesMedicineHumans030212 general & internal medicineeducationGaitPostural BalanceAgededucation.field_of_studyRehabilitationbusiness.industryRehabilitationPosturographyParkinson DiseaseResistance TrainingDeporteMiddle Agedmedicine.diseaseExercise TherapyTreatment OutcomeEnfermedad de ParkinsonSpainPhysical therapyParkinson’s diseaseFemalemedicine.symptombusiness030217 neurology & neurosurgeryFollow-Up StudiesEuropean journal of physical and rehabilitation medicine
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Does Music Therapy Improve Anxiety and Depression in Alzheimer's Patients?

2017

OBJECTIVE: To evaluate the effectiveness of the implementation of a short protocol of music therapy as a tool to reduce stress and improve the emotional state in patients with mild Alzheimer's disease. METHODS: A sample of 25 patients with mild Alzheimer's received therapy based on the application of a music therapy session lasting 60 min. Before and after the therapy, patient saliva was collected to quantify the level of salivary cortisol using the Enzyme-Linked ImmunoSorbent Assay (ELISA) immunoassay technique and a questionnaire was completed to measure anxiety and depression (Hospital Anxiety and Depression Scale). RESULTS: The results show that the application of this therapy lowers th…

Malemedicine.medical_specialtyMusic therapyHydrocortisoneTerapéuticaEnfermedad del sistema nerviosoDiseaseAnxietyHospital Anxiety and Depression Scale03 medical and health sciences0302 clinical medicineAlzheimer DiseasemedicineHumansIn patientAlzheimer Enfermedad de030212 general & internal medicineSalivaPsychiatryMusic TherapySalivary cortisolDepression (differential diagnoses)AgedAged 80 and overDepressionbusiness.industryComplementary and alternative medicineTerapiaPhysical therapyAnxietyImmunoassay techniqueFemalemedicine.symptombusinessEnfermedad mental030217 neurology & neurosurgeryMúsica
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